Reza Gharemohammadlou
*, Ali Emad
1 Department of Pulmonary Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
Abstract
Background and objectives: Bronchiectasis is a late complication of mustard gas exposure with disturbing symptoms in its victims. There are some reports of successful treatment with prolonged effect of the symptoms by local steroid installation. In this study we evaluated the efficacy of local steroid installation in a group of musterd gas victims during the IRacl war. Material and method: This was an interventional pre – post treatment exposure study. We evaluated the effects of local steroids in 10 bronchiectasis patients by installation of steroid via bronchoscope. We measured lung volumes and airway resistance before procedure and again two weeks and three months after treatment implementation. Then we compared the results of three consecutive measurements. Friedman analysis was used for statistical analysis. Results: There was no important improvement in airway resistance; lung volumes and airflows after procedure, although treatment of bronchiectasis with local installation of steroids had no important complications. Of spirometric indices, only SReff was followed the substantial and significant increase Conclusion: Local steroids are not effective treatment for mustard gas induce bronchiectasis.