Comparison of the Effects of Eight-week Endurance Training, Resistance and Garlic Extract Supplementation on MDA and TAC in Rats with Metabolic Syndrome

Abstract

Background & Objectives: In accordance with the limited studies on the effects of eendurance (ET) and resistance (RT) training with and without the garlic extract (GE) on metabolic syndrome, this study was conducted to identify and compare the effects of eight-weeks ET, RT and GE supplementation on malondialdehyde (MDA) and total antioxidant capacity (TAC) in rats with metabolic syndrome. Materials and Methods: 48 rats with metabolic syndrome (12-weeks, weight range of 310 to 350 g) in a randomized design were allocated into six equal groups: control (n=8), ET (n=8), RT (n=8), ET+GE (n=8), RT+GE (n=8), GE (500mg/kg, n=8). After familiarization of the rats with metabolic syndrome, 8-weeks (3 sessions a week) in an exercise protocol (ET, RT) with or without GE. Data were analyzed using one-way ANOVA and Bonferroni (Sig˂0.05). Results: The results show that ET and RT with GE consumption have significant effect on stress oxidative indices (TAC and MDA). Conclusion: Endurance and resistance training along with GE consumption can increase the TAC base, reduce unfavorable changes in serum MDA syndrome.