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Med J Tabriz Uni Med Sciences. 2023;45(4): 376-382.
doi: 10.34172/mj.2023.040
  Abstract View: 915
  PDF Download: 256

Clinical Neuroscience

Case Report

Evaluating the diagnosis and treatment of neuro-Behçet’s disease with cascade sign appearance in brainstem: a case report

Samaneh Hosseini 1* ORCID logo, Alireza Khabazi 2 ORCID logo, Mehran Ghaffari 3 ORCID logo, Seyed Hossein Aghamiri 3 ORCID logo

1 Neuroscience Research Center, Department of Neurology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
2 Connective Tissue Diseases Research Center, Department of Internal Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
3 Department of Neurological Diseases, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Tehran, Iran
*Corresponding Author: Email: dr.hosseini.neurologist@gmail.com

Abstract

This study aimed to investigate a case of neuro-Behçet’s disease misdiagnosed as acute ischemic stroke or multiple sclerosis (MS). The studied case was a 29-year-old man with subacute onset of hemiparesis, dysarthria, and ataxia who was diagnosed as acute ischemic stroke at first. Due to no significant improvement, the patient was managed as an MS case, but he did not experience any improvements again. We noticed a history of oral and genital aphthous and cascade sign appearance in his brain MRI. Then, Behçet’s disease with secondary parenchymal involvement of brainstem was confirmed. The patient received infliximab, which resulted in clinico-radiological recovery.

Practical Implications. Given the prevalence of Behçet’s disease in the Middle East, the possibility of its diagnosis should be considered in patients with atypical history or imaging for ischemic stroke or MS.



How to cite this article: Hosseini S, Khabbazi A, Ghaffari M, Aghamiri S H. Evaluating the diagnosis and treatment of neuro-Behçet’s disease with cascade sign appearance in brainstem: a case report. Med J Tabriz Uni Med Sciences. 2023; 45(4): doi: 376-382. 10.34172/mj.2023.040. Persian.
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Abstract View: 916

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Submitted: 05 Apr 2023
Revision: 14 May 2023
Accepted: 14 May 2023
ePublished: 09 Sep 2023
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