Azim Rezamand
1, Saeid Aslanabadi
2, Laleh Alizadeh
3, Mohammadamin Rezazadehsaatlou
4*1 Department of Pediatric Hematology, Children's Hospital, Tabriz University of Medical Sciences, Tabriz, Iran
2 Children's Hospital, Tabriz University of Medical Sciences, Tabriz, Iran
3 Genral Practitioner
4 Tuberculosis and lung Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Abstract
Background and Objectives: Spleen is known as the largest lymphoid organ in human body and is responded orthe blood filtration; strengthen the immune system activity, hematopoiesis. Trauma and congenital problems are the most common indications for splenectomy. The aim of this study was evaluation the ten-year indications of splenectomy in Tabriz Children's Hospital. Materials and Methods: In this retrospective study that the hospital recors of all cases who underwent splenectomy in Tabriz Children's Hospital was studed and the indications of splenectomy in these children evaluated. Results: Thirty four children were boys and 35 of studied children were girl. Mean age of boy children was 99.20 ± 42.77 months and the mean age of girl children was 125.42 ± 35.24 months (P=0.007). Major beta-talassemia (n=23) was the most common indication for splenectomy in studied children. Spleen size in 22 children was normal and in 47 children spleen size was great. Platelet drop in two cases, port vein thrombosis in 3 cases, heard failure in two cases, sepsis, recurrent meningitis, sepsis and CVA in one of the studied children were postoperative complication of study. Only seven cases of studied children were died after surgery that two cases of mortality causes was heart failure due to talassemia. In our study, trauma in 3 cases (4.34%) of the studied children was the splenectomy indications that one of these children had died. Conclusion: Major beta-talassemia, hereditary spherocitosis and idiopathic thrombocytopenic purpura were the most common causes of spelenctomy in the studied children and in our study, 5 of children with talassemia were died that 2 causes was heart failure due to talassemia, 2 cases due to port vein thrombosis and one case due to CVA. Postoperative complication rate was 23.18% and risk of infection and sepsis in our study was 3.07% and also the mortality rate in our study was 10.1%.