Heybatollah Borghei
1, Jalal Mehdizade
1, Seyed Javad Seyed Toutounchi
2*, Leila Azarmi
2, Nagisa Seyed Toutounchi
31 Department of E.N.T, School of Medicine, Tehran University of Medical Sciences, Tabriz, Iran
2 Department of E.N.T, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
3 School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
Abstract
Backgrounds and Objectives: Laryngeal cancer is one of the most common cancers of head and neck and its metastases to the lymph nodes are the main problem in the management of disease either for surgeon or in patient for its beauty problem. Materials and Methods: The purpose of this study was to evaluate the rate of neck lymph nodes metastasis in patients with laryngeal cancers based on tumor histopathology. In a descriptive-analytical study that performed on 200 patients with laryngeal cancer, rate of neck lymph nodes’ metastasis was evaluated and necessary information such as histopathology of laryngeal tumor was collected from patients’ records. Data were analyzed by statistical methods. Results: From total number of 200 patients, 197 were male, with the total mean age of 56.53±7.89 years. Seventy eight of patients had neck metastasis. Two patients had insitu squamous cell calcinoma (SCC) without neck metastases, 117 patients had well differentiated SCC with 10.3% neck metastases, 55 patients had moderately differented. SCC with 74.5% neck metastases, 19 patients had poorly diff. SCC with 100%neck metastases, 6 patients had undifferentied. SCC with 100% neck metastases and one patient had Verocos carcinoma without neck metastases. Conclusion: Neck lymph nodes metastases in patients with laryngeal cancer is a common findingthat rates of it dependents on the site, size and tumors histopathology and degree of differentiation.