Abstract
Background & objective: Scalp hair is very important from cosmetic aspects in addition to barrier function, so alopecia may result in psychiatric complications. Androgenetic alopecia is one of the most important categories that many of topical and systemic therapies have significant side effects. This survey has comopared effectiveness of 2% minoxidil solution with 2% progesterone solution.
Methods and Materials: Seventy female patients with female pattern androgenetic alopecia were selected .Thirty five patients applied 2% topical progesterone, 2ml daily, and 35 patients applied 2% minoxidil solution 2ml daily for a year. All patients admitted monthly for follow up assessment according to subjective and objective (increase in hair number per centimeter square) aspects.
Results: In 85% of patients who applied 2% minoxidil hair loss stopped and new hair grew. 71% of other group had same results (P=0/145).
Conclusion: Topical progesterone is an effective, cheap and available therapy for treatment of androgenetic alopecia, so more surveys about its effectiveness are necessary.