Abstract
Background and objective: Resistance to antibiotics used in routine treatment of urinary tract infections (UTIs) is ever increasing worldwide. Therefore information about susceptibility of strains causing UTIs is important. Nowadays ciprofloxacin as a new quinolone is a very important agent against bacteria isolated from UTIs. This study was performed to evaluate the susceptibility of the isolated strains against this valuable antibiotic.
Material and methods: In present study, out of 571urine samples 122 Gram negative and Gram positive bacterial strains isolated. All the isolates were identified by biochemical test, Gram stain and Susceptibility tests by disk agar diffusion method and MIC determination.
Results: Our results indicate that the most prevalent bacteria isolated from UTIs were E. coli(63.9%) followed by S. aureus (29.9%). Isolated E. coli and S. aureus strains showed resistance to ciprofloxacin in 17.9% and 14.2%, respectively.
Conclusion: Our results showed that resistance to ciprofloxacin is relatively high in our bacterial strains isolated from UTIs and can cause therapeutic problems. Therefore monitoring of resistance, especially monitoring of MIC of the isolated strains could be beneficial in using ciprofloxacin as a valuable antibacterial agent in treatment of UTIs.