Abstract
Focal epithelial hyperplasia ( Heck disease) is a rare benign and contagious lesion that first time was reported in children of Eskimos and American Indian. Up to now only one case report of this lesion has been reported from Iran. High incidence of this lesion among family members indicates infectious pathogenesis. Human papilloma virus (subtype 13 and 32) has known as cause of this lesion. FEH usually characterizes by multiple soft nodules and papules in the oral mucosa specially on lips, buccal mucosa and the lateral border of the tongue. This article reports the first case of FEH in Tabriz and the second one in Iran.