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Med J Tabriz Uni Med Sciences Health Services. 2020;41(6): 91-97.
doi: 10.34172/mj.2020.011
  Abstract View: 431
  PDF Download: 138

Original Article

Comparison of effects of Chlorhexidine mouthwash with Herbal Cinnamol mouthwash on prevention of ventilator associated pneumonia

Sayed Taghi Hashemi 1 ORCID logo, Babak Alikiaii 1* ORCID logo, Mohammad Ali Fallah Medvari 2 ORCID logo, Fatemeh Karimi 2 ORCID logo, Abolfazl Fallah Medvari 2 ORCID logo

1 Department of Anesthesiology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
2 Isfahan Medical Faculty Research Center, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
*Corresponding author; E-mail: alikiaiib@med.mui.ac.ir

Abstract

Background: Ventilator associated pneumonia (VAP) is a prevalent infection of intensive care unit(ICU) accompanied with increased rate of complications and mortality. This study is raised with the aim of comparing effects of Chlorhexidine mouthwash with Herbal Cinnamon mouthwash on prevention of ventilator associated pneumonia among patients hospitalized in ICU.

Methods: Number of eighty-six patients admitted at ICU was divided into two 43-member groups. First group underwent moth washing using Chlorhexidine mouthwash2% and 2nd group underwent mouth washing using Herbal Cinnamol mouthwash. Frequency and onset of VAP incidence were compared in two groups.

Results: Groups under treatment with Cinnamol and Chlorhexidine were not different considering demographic factors (P>0.05). In Cinnamol group, 25(58.13%) and in Chlorhexidine group, 27(62.79%) had pneumonia. Incidence of VAP was not different in two groups (P=0.826). In Cinnamol group, 32% of patients presented VAP prior to fifth day of ventilation and 68% after fifth day and in Chlorhexidine group 22.22% prior to fifth day and 77.77% after fifth day. VAP onset was not significantly different among two groups (P=0.536).

Conclusion: Chlorhexidine mouthwash in comparison to Cinnamol mouthwash for prevention of VAP among patients admitted at ICU presented no superiority considering considering decrease in VAP incidence and onset.

Keywords: Chlorhexidine, Cinnamol, Ventilator Associated Pneumonia, Mouthwash
How to cite this article: Hashemi S T, Alikiaii B, Fallah Medvari M A, Karimi F, Fallah Medvari A. [Comparison of effects of Chlorhexidine mouthwash with Herbal Cinnamol mouthwash on prevention of ventilator associated pneumonia]. Med J Tabriz Uni Med Sciences Health Services. 2020 February- March; 41(6):91-97. Persian.
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Submitted: 04 Apr 2018
Accepted: 13 May 2018
ePublished: 19 Dec 2019
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