Logo-mj
Med J Tabriz Uni Med Sciences Health Services. 2020;42(5): 547-555.
doi: 10.34172/mj.2020.078
  Abstract View: 1967
  PDF Download: 312

Original Article

Short and long-term mortality in severe sepsis/septic Shock in a setting with low antibiotic resistance centers

Parviz Saleh 1 ORCID logo, Zeinolabedin Khodaie 1* ORCID logo, Negar Mohtadi 1 ORCID logo

1 Department of Infectious and Tropical Disease, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
*Corresponding Author: *Corresponding author; E-mail:, Email: khodaie.z.99@gmail.com

Abstract

Background: Sepsis, which is a common inflammatory response to severe infection, is one of the major causes of mortality in hospitalized patients. Sepsis, severe sepsis or sepsis syndrome, and eventually septic shock, may be seen in the development of infection. The aim of this study was to evaluate the short-term and long-term mortality in patients with severe sepsis and septic shock in centers with low antibiotic resistance.

Methods: In this cross-sectional study, blood culture samples and peripheral blood samples were taken from all patients for para-clinical tests. The severity of severe sepsis and septic shock was assessed by the APACHE II and SOFA clinical criteria. Sepsis risk factors and primary causes of sepsis were recorded.

Results: From 100 patients, 55% had severe sepsis and 45% had septic shock. SOFA24h and SOFA96h scores were significantly higher in patients with septic shock. The most common primary cause of sepsis was related to abdominal infections with a frequency of 42%. The frequency of confirmed positive blood culture was 53%. The most commonly isolated pathogen was E.coli with a frequency of 66%. Short-term mortality was 29% and long-term mortality was 28.2%.

Conclusion: The main risk factors affecting the mortality of patients were age-related septic shock, cardiovascular disease; hypertension, immunosuppression, and SOFA score.



How to cite this article: Saleh P, Khodaie Z, Mohtadi N. [Short and Long-term Mortality in Severe Sepsis/Septic Shock in a Setting with Low Antibiotic Resistance Centers]. Med J Tabriz Uni Med Sciences Health Services. 2020-2021;42(5):547-555 Persian.
First Name
 
Last Name
 
Email Address
 
Comments
 
Security code


Abstract View: 1968

Your browser does not support the canvas element.


PDF Download: 312

Your browser does not support the canvas element.

Submitted: 25 Mar 2019
ePublished: 30 Dec 2020
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)