Abstract
Background: Considering the increased rate of obesity and diabete and their relationship with liver disease this research was performed to determine the effect of eight weeks endurance training with chlorella supplementation on serum levels of liver enzymes in type 2 diabetic middle aged women.
Methods: In this semi experimental research, 40 non-athletic type 2 diabetic women (45-65 years old) with BMI greater than 25 were voluntarily divided into four groups: control, chlorella supplementation, endurance training and endurance training with chlorella. Training group performed walking and running three sessions a week for eight weeks, with an intensity of 65%-85% of maximum heart rate for 25 to 40 minutes. Chlorella group consumed chlorella capsule at a dose of 600 mg two times a day. 24 hours before and 48 hours after training, 5cc blood samples were taken from the brachial vein in the fasting state to measure liver enzymes including: Alanine transaminase (ALT), Aspartate transaminase (AST), and Alkaline phosphatase. One-Way ANOVA test was used to evaluate the effectiveness of the exercise protocol. All statistical test were performed considering p<0.05 meaningful.
Results: Ther was a significant difference among control and cholorella group after 8 weeks training on the enzymes AST and ALP: (respectively p=0,004 , p=0,006) .Also variations of enzym ALT in chlorella and endurance training+chlorella groups had a meaningful difference with control group (respectively p=0,022 , p=0,027).
Conclusion: The chlorella supplementation decreases liver enzyme levels in type 2 diabetic patients and can be helpful in treating of fatty liver type 2 diabetic subjects.