Parvin Farzanegi
1, Masoumeh Habibian
2, Mirabdollah Tahramuzi
1*, Maryam Keshvari
31 Department of Exercise Physiology, Sari Branch, Islamic Azad University, Sari, Iran.
2 Department of Physical, Education, Qaemshahar Branch, Islamic Azad University, Qaemshahar, Iran.
3 PhD student in exercise physiology, Department of Physical Education and Sport Sciences, University of Lorestan, Khorramabad, Iran.
Abstract
Background: The aim of this study was to determine the Effects of aerobic training on Apelinergic system of heart tissue in aged rats.
Methods: In this study 14 elderly wistar rats with average age of 40-50 months old, were randomly divided into two groups: control and training. Swimming training was programmed 3 days /week, 30 min/day for 8 weeks. All rats were sacrificed 48 hours after the final training session and after 24 hours of fasting myocardial tissue, apelin and its receptor levels were determined using ELISA method.
Results: No significant difference was found between control and experimental group apelin heart muscle tissue there (p=0.01). Also, the apelin receptor test for heart tissue between the two groups was significant (p=0.02). Pearson correlation analysis between apelin and its receptor in the control group was statistically significant inverse linear (p=0.01), But the test for the exercise group showed no significant relationship (p= 0.44).
Conclusion: It is possible that aerobic training in older people with varying levels of apelin and its receptors in heart muscle tissue, improves the cardiovascular system of the people.