The Effect of Six-Months Aerobic Exercise with Moderate Intensity on IL1β, TNF-α, and Brain volume in 50-65 Years Old Women with Syndrome Metabolic

Abstract

Background: The aim of this research was to evaluate the effect of six months aerobic exercise with moderate intensity on IL1β, TNF-α, and brain volume in 50-65 years old women with syndrome metabolic. Methods: 24 women with metabolic syndrome (MetS) took part voluntarily and divided in tow group MetS exercise (ME), MetS control (MC). ME group participated in an aerobic exercise training (AT) program (six month), tree session per week, each session contain tree performing part and tow rest part. Also blood samples were conducted before and after six months training for evaluate levels of IL1β, TNF-α. Brain volume measured by MRI. Results: IL1β, and TNF-α after six month aerobic exercise significantly decreased (P˂0.05). Brain volume after six month didn’t significantly changed (P˃0.05). Conclusion: With modulating the time and the intensity of exercise can affect the Brain volume.