Saeed Dabbagh Nikukheslat
1, Farhad Gholami
2*, Yaghoub Salek-Zamani
3, Afshar Jafari
1, Esmaeil Faraji
41 Department of Exercise Physiology, School of Physical Education and Sports Sciences, Tabriz University, Tabriz, Iran
2 Department of Exercise Physiology, School of Physical Education and Sports Sciences, Shahrood University of Technology, Shahrood, Iran
3 Department of Physical Medicine and Rehabilitation, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
4 Department of Endocrinology and Metabolism, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
Abstract
Background: Diabetes is one of the main causes of neuropathy. Metabolic control is essential to hinder its process. The present study was designed to investigate the effect of aerobics training on metabolic control in type-2 diabetic men with peripheral neuropathy.
Methods: Twenty-four male subjects with Type 2 Diabetes were randomly assigned into two groups (each group comprised of 12 subjects): 1- Aerobics training (43±6.4 yrs, 86.5±15.3 kg) 2- control (42±4.6 yrs, 89.3±11.9 kg). Aerobics training consisted of 20 to 45 minutes walking and running with 50 to 75 percent of heart rate reserve, three sessions per week for 3 months. Before and 48h after last training session, body composition measurements were performed and then fasting and after-meal blood samples were taken.
Results: We observed no significant changes in weight, fat percentage and body mass index following intervention (P>0.05). Furthermore, fasting and OGTT glucose and HbA1C levels significantly decreased and lipid profile improved significantly (P<0.05). We also observed significant inter-group difference only for HbA1C and HDL-C (P<0.05).
Conclusion: Based on the findings of the present study, it could be concluded that aerobic exercise regimen could be a safe non-pharmacological strategy to achieve an optimal metabolic control in type-2 patients with peripheral neuropathy.