Mohammad Reza Khani
1, Reza Bigdeli
2, Hosssein Vazini
3*, Parmis Notghi
41 Department of Physiology, School of Sciences, Islamic Azad University, Science and Research Zanjan Branch, Zanjan, Iran
2 Department of Physiology, School of Sciences, Shahid Beheshti University, Tehran, Iran
3 Department of Nursing, School of Basic Science, Islamic Azad University, Hamedan Branch, Hamedan, Iran
4 Department of Biology, School of Basic Science, Islamic Azad University, Hamedan Branch, Hamedan, Iran
Abstract
Background: Lead (Pb) is a one of the well-known dangerous contaminant Lead can cause disorders in the process of spermatogenesis. Using medicinal plants to cure impotence and lack of sex cells can have a positive effect. In this study, parsley extract on spermatogenesis in male rats which have received lead acetate is investigated.
Methods: In the present study, 36 rats were divided into 6 groups of 6. Animals received lead acetate and extract of parsley for a period of 28 days. After 28 days, animals were weighted and were anesthetized by ether, then the body and testis were weighted and numbers of spermatocytes, spermatogonia, Leydig cells were studied. The obtained results were analyzed by ANOVA and Tukey tests.
Results: Lead acetate significantly decreased the spermatocytes, spermatogonia, Leydig cells. Parsley extract with 200 mg/kg dose could lead to a significant increase of sperms in the tube lumen (p<0.05).
Conclusion: Parsley’s extract effect on spermatogenesis in male rats which received lead acetate was justified.