Seyed Ebrahim Hosseini
1*, Davood Mehrabani
2, FatemehAlSadat Razavi
11 Department of Biology, Shiraz Branch, Islamic Azad University, Shiraz, Iran
2 Director of Stem Cell and Transgenic Technology Research Center, Ghadir Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
Abstract
Background & Objectives: Infertility in men is mainly caused by as low or abnormal spermatogenesis and hormonal problems. Because of high costs and potential side effect of routine therapeutic modalities. It seems that use of herbal medicine have fewer side effects; the aim of the study is to examine the effect of palm pollen extract on serum levels of hormones and spermatozoa dynastic cells in adult male mice. Materials & Methods: This experimental study was conducted on 40 adult male rats. They were divided into 5 groups 8, in each group that included controls (no treatment), only saline treated and three experimental groups that received aqueous extract of date palm pollen in three different dosages, doses 100, 200 and 400 mg / kg respectively. All prescriptions were done intraperitoneally for 35 days. At the end of experiment animals were phlebotomized from the heart and by separation of serum samples, amounts of testosterone, estrogen, progesterone were counted, and by separation of testicle, the numbers of spermatogonia, spermatocytes and spermatid were counted and the results were analyzed using unilateral ANOVA and Duncan methods. Results: The results showed that aqueous extracts of palm pollen dose-dependently caused significant increasing the levels of estrogen, progesterone and testosterone and increasing the numbers of spermatocytes and spermatid. Conclusions: The presence of compounds such as cadmium, zinc, steroids, flavonoids, saponins, lipids, and by substances that inhibiting the enzyme 5- alpha redoctase could increase testosterone and sexual dynastic cells.