Ehsan Mir
1, Mehrdad Fathei
1*, Mojtaba Mir Sayeedi
2, Keyvan Hejazi
11 School of Physical Education and Sports Sciences, Ferdowsi University of Mashhad, Mashhad, Iran
2 School of Physical Education and Sports Sciences, Islamic Azad University of Kalale, Kalale, Iran
Abstract
Background and Objectives: Several studies have showed that high levels of CRP and homocysteine increase the risk of coronary artery diseases. This study was aimed to investigate the effects of combined exercises on homocysteine, CRP and lipid profile in middle-aged inactive men. Materials and Methods: In this semi-empirical study, 24 subjects were selected by convenience sampling method. The cases were randomly assigned into two groups [experimental (n=12) and control (n=12)]. The aerobic training method included: 3 times a week, 20 minutes per session, with intensity of 60-70 percent of heart rate reserve. Also the resistance training program conducted by intensity of 70% one repetition maximum. Results: The levels of serum homocysteine and CRP after combined exercises were decreased significantly (P=0.001 and P=0.003, respectively). Although, TC, TG, HDL-C and LDL-C levels between both groups did not differed significantly. As well as, maximum oxygen consumption has increased significantly (P=0.008). Conclusion: It seems that combined exercise (aerobic and resistance) with reduction of homocysteine and CRP levels can used as a non-pharmacological methods to prevent the development of atherosclerosis.