Sahar Badie
1*, Mohammad Heydarzade
2, Abdollah Janatdoost
2, Farzad Ilkhchoyi
11 Children Hospital Research Center, Department of Pediatrics, Tabriz Children Hospital, Tabriz, Iran
2 Department of Pediatrics, Al-Zahra Hospital, Tabriz, Iran
Abstract
Background and Objectives: Respiratory Distress Syndrome (RDS) is an important cause of neonatal mortality and morbidity. Lamellar Bodies Cells (LBC) count has been introduced for RDS diagnosis. The aim of this study was to determine the validity of this method. Materials and Methods: Eighty-two premature neonates entered to this crossectional study, all their clinical and imaging information was obtained. Patients with distress syndrome criteria were marked. Gastric aspiration were performed and LBC were counted by sysmex, Xs 800 cell counter in all cases. Results: The mean weigh of neonates was 1745±515 grams. The frequents of patients with and without RDS criterias were 33(40/24%) and 82(59/75%), respectively. LBC count in RDS and non RDS group was not differed significantly. (160±135 vs 151 ± 143 per microliter, P= 0.9). The sensitivity and specificity of LBC for RDS in cut off point of 80000 per microliter was 69% and 45%, respectively (P> 0/05). Conclusion: Based on clinical and imaging diagnostic tests for RDS, the LBC counting cannot be a reliable test for RDS prediction.