Prevalence of Metabolic Syndrome in 18 to 40 Years Old Offspring of Persons with and without Ischemic Heart Diseases

Abstract

Backgrounds and Objectives: Metabolic syndrome is a collection of risk factors which finally increase the risk of ischemic heart disease and type 2 diabetes mellitus in affected individuals. Our aim was to assess whether the presence of ischemic heart disease in parents increase make people the risk of metabolic syndrome in offspring’s or not? Materials and Methods: 137 persons aged 18 to 40 with a positive history of ischemic heart disease in their fathers، mothers or both were selected as the case group. Another group of 132 persons without a history of ischemic heart disease in their parents were selected as the control group. Metabolic syndrome was diagnosed based on ATP III (Adult Treatment Panel III) criteria considering high blood pressure، central obesity، impaired fasting glucose، high triglyceride level and low HDL-C levels. Results: The prevalence of metabolic syndrome in offspring of subjects with and without ischemic heart disease did not show any significant difference (14.0% vs. 11/5%; p > 0.05). Comparison of the prevalence of metabolic syndrome in male and female subjects also did not show any significant difference (16.7% vs. 15.2%; p > 0.05 for females and 11.4% vs. 2.6%; p > 0.05 for males). Conclusion: The present study does not reveal any identifiable difference in the prevalence of metabolic syndrome in offspring of persons with and without the history of ischemic heart diseases; however، this does not diminish the importance of metabolic syndrome in offspring of patients with ischemic heart disease.

Keywords: Ischemic heart disease, Metabolic syndrome x, Blood glucose, Acute coronary syndromes