Abstract
Background and Objectives: Acne is a common skin disease that if remains without treatment, permanent scars and pigmentation would be anticipated.These complications which affect mostly adolescents and young adults may lead to some important psychosocial Problems. Comedo formation has a basic role in the inflammatory lesions and permanent acne scar. With regard to the mechanism of superficial peeling that can be attributed to the disconnection of the bands between keratinocytes, Jessner solution can be used in treatment of comedon and acne.
Materials and Methods: This study was performed on 15 patients with mild to moderate acnes. The patients enrolled, were treated with Jessner solution in 4 sessions with one week intervals. The surface should be washed with alcohol before treatment. After appearing the erythema the procedure must be stopped and the solution be washed off Patients should be advised to use sun block creams. Jessner solution is composed of various compounds such as salicylic acid 4% resorcinol 14% lactic acid 14% in the ethanol base.
Results: In this study we compared the numbers of comedones, pustules and inflammatory papules in frontal area before and after treatment. The patients were also observed for probable complications. The result obtained in this study showed that the average number of comedones in the frontal area were 72.73 before and 36.93 after treatement. The average erythematous papules of face were 32.4 and 20.46 before and after treatment respectively. The average number of face pustules numbers reduced from 9.13 before treatment to 6.4 after that. In the aggregates, the number of comedones, erythematous papules, and pustules reduced significantly in this study. No especial complications were observed in our study.
Conclusion: Regarding the simplicity, cost effectiveness of this method and also its safety, this procedure can be an appropriate alternative for treatment of acne.
MJTUMS, NO. 64, 45-48, 2005