Med J Tabriz Uni Med Sciences Health Services. 2005;27(1): 33-36.
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Evaluation of Serum Sodium and Ionized Calcium Levels in Febrile Convulsions

*Corresponding Author: Email: Sakhak@tbzmed.ac.ir


Background and Objectives: Febrile convulsion (FC) is the most common type of seizure in childhood.The most important factors affecting the incidence of febrile convulsion are age , fever and genetic base. As sodium is important factor in neuronal cell depolarization and production of electrical discharge and finally seizures, we evaluated correlation between serum sodium and ionized calcium in febrile convulsion. Materials and Methods: In this study two groups (53 patients as case and 53 patients as control group)were studied.The case group had fever (at least 38ºC) and convulsion for the last 24 hours. Control group had the same characteristics but without convulsion. Serum sodium and ionized calcium were determined in both groups before any therapeutic procedures be established, and results were statistically analyzed. Results:In exposure groups the mean serum sodium level was135.4 ± 4 meq/l, lower than control groups (137.94 ± 2.92).There was statistically significant difference between two groups(P<0.001).But serum ionized calcium in two groups had no meaningful difference(P=0.460). Conclusion: Although sodium plays an important role in cell physiology and neuronal stimulation in developing seizure, according to the study and literatures as well, it would be better to conduct extensive studies on the likliehood of correlation between serum sodium level and febrile convultions.
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Submitted: 09 Jul 2013
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