Abstract
Background and Objectives: Probable predicting factors of ovarian response include age and body mass index (BMI), ovarian volume, number of antral follicles and the hormonal markers. The available data is heterogeneous and sometimes conflicting in this regard. The aim of this study was to evaluate some predicting factors of ovarian response during IVF cycle.
Materials and Methods: In an analytic cross-sectional study, 100 female candidates of IVF were recruited in Tabriz Alzahra Infertility Center during a 14-month period. Ovarian response was categorized and evaluated in two sections according to the number of retrieved follicles (≤10 and >10) and oocytes (appropriate response: 5-14 oocytes, inadequate: ≤ 4 oocytes, excessive response: ≥ 15 oocytes). Patient’s age and BMI, as well as smoking status, and ovarian volume, number of antral follicles and serum FSH, LH and estradiol levels were evaluated as predictive parameters of ovarian response.
Results: Ninety six women with a mean age of 29.8±5.9 years were enrolled. Significant predictors of inadequate number of retrieved follicles were older age, high BMI and high basal serum FSH and low number of antral follicles.
Conclusion: Significant predictors of inadequate number of retrieved oocytes were older age, high BMI and basal serum FSH, longer duration of infertility, and low ovarian volume and serum estradiol. Smoking, level of serum LH and number of antral follicles were not significantly related with the number of retrieved oocytes. The current data can be used for prediction of ovarian response in patients undergoing IVF cycle.