Abstract
Background and Objectives: Giant cell lesions account for approximately 7% of all benign tumors of the jaws. The demographic characteristics of giant cell lesions vary in different populations. The aim of this study was to analyze epidemiology of giant cell lesions in Rasht between 1379 and 1387.
Materials and Methods: This descriptive-cross sectional and retrospective study was based on data in pathology archives. Medical files of patients with diagnosis of giant cell lesion from Razi, Afrah and Poursina laboratories (referral laboratories for oral and maxillofacial specimens) were assessed. Data of age, gender and site of lesion were recorded.
Results: Twenty five cases of central giant cell granuloma (CGCG) and 74 cases of peripheral giant cell granuloma (PGCG) were found. The mean age of the patients was 25 15.5 and 45.27 17.4 years in CGCG and PGCG, respectively. Fifty six percent of CGCG cases and 56.3% of PGCG cases were females.
Conclusion: Giant cell lesions comprised 4.2% of the oral lesions. Peripheral lesions found in older adults and females indicate the necessity of more evaluation about etiologic factors related to the females and older adults.