Abstract
Background and objective: Brainstem auditory evoked potentials (BAEPs) are a set of seven positive waves recorded from the scalp during the first 12 millisecond following a click; BAEPs are effective in evaluation the integrity of peripheral and central auditory pathways. Chronic renal insufficiency leads to hearing organ damage due to toxic influence of nitric compounds, electrolyte disorders and ototoxic materials. The aim of this study is evaluation of hearing organ function with BAEPs in patients with chronic renal failure under hemodialysis.
Materials and Methods: This study is a case-control and analytical study. Forty patients with CRF under hemodialysis in Tabriz Imam hospital and 40 individuals without CRF were selected. We used BAEP test in both of them. The data was analyzed with SPSS11 and independent- sample t-test and Chi- Square tests.
Results: There was a significant difference between two groups in BAEP changes, in III, IV,V waves and I- III and III-V intervals (P < 0.05). There was no correlation between duration of dialysis and BAEP changes. A significant correlation was found between potassium of serum and BAEP changes (P < 0.05). There was no correlation between BAEP changes and other laboratory amounts (P > 0.05).
Conclusion: The elongation of wave III and V, and I-III and III-V interval in BAEP have been demons trated in other studies. Our study is consistent with those studies. Hemodialysis dose not permanently improve hearing, but it may temporarily prevent its further deterioration. BAEP test may use for monitoring hearing organ damage in course of uremia.