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Med J Tabriz Uni Med Sciences Health Services. 2007;29(3): 71-75.
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  PDF Download: 117

Cardiovascular System

Research

Delays in Administration of Streptokinase in Patients with Acute Myocardial Infarction Hospitalized in Shahid Madani Hospital of Tabriz University of Medical Sciences

SAMADIKHAH J, ALIZADE M, REZAEIFAR P*, AHADPOUR A, EBRAHIMI B H
*Corresponding Author: Email: par496@yahoo.com

Abstract

Background and Objectives: Acute Myocardial Infarction is one of the most common diseases all over the world and the first cause of death in Iran. Reperfusion therapy is the cornerstone of the effective treatment of these patients. Early thrombolytic therapy leads to better coronary reperfusion and a greater reduction in mortality and reinfarction rates. The main purpose of this study is to determine and compare the different time intervals before and after arriving at hospital in both groups who received thrombolysis (T+) and did not receive thrombolsis (T-). Methods and Materials: This was a cross sectional comparative study carried out in Shahid Madani Hospital of Tabriz University of Medical Sciences. We randomly assigned 150 patients with acute myocardial infarction with elevation of ST segment, in 2 groups with and without administration of thrombolysis. Results: Mean onset–to–call time in T+ group was less than T- group.15% of patients had call–to–needle time less than 90 minutes and in over the 90% of patients, door–to–needle time was greater than 30 minutes. Conclusion: significant pre–hospital delay and considerable in–hospital delay shows necessity of thrombolytic therapy pre–hospital or as soon as possible early after entering emergency room.
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Submitted: 03 May 2010
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