Abstract
Background and objectives: Asthma is a chronic inflammatory disease of airways that results from complex interaction of genetic and environmental factors and its prevalence is increasing. As the high prevalence of the disease, detection of risk factors is necessary.althoug there are many studies about subject in different parts of world, but differences in prevalence and risk factors in different countries and ethnics, necessitate conducting of this study.
Methods and material: in a case-control study 120 patients with persistent asthma and 2-8 years old age group and 240 non-asthmatic children at the same age as control group were selected. The asthma risk factors were compared in two groups .Data was analyzed with spss12, chi square and T-test. The significant level was defined as p<0/05 in this study.
Results: there was significant differences between two groups in risk factors such as low birth weight (P<0.001, OR=3.54), Rhinitis (P=0.005, OR=2.05), breast feeding (P=0.001, OR=5.4), family history of asthma (P=0.003, OR=7.5) and Passive smoking (P=0.001, OR=2.36).
Conclusion: In this study risk factors of asthma was assessed and the most important factors were history of asthma in first degree family, non breast-feeding and low birth weight respectively.