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Med J Tabriz Uni Med Sciences. 2021;43: 173-178.
doi: 10.34172/mj.2021.042
  Abstract View: 258
  PDF Download: 140

Original Article

Evaluation of maternal factors for the development of retinopathy of prematurity

Amir Eftekhari 1 ORCID logo, Vahideh Manouchehri 1* ORCID logo, Farideh Mosavi 1 ORCID logo, Mohammad Ali Jahanbani 1 ORCID logo

1 Department of Ophthalmology, Tabriz University of Medical Sciences, Tabriz, Iran
*Corresponding Author: Email: manouchehriv@tbzmed.ac.ir

Abstract

Background: Since Retinopathy of prematurity (ROP) is a leading cause of childhood blindness, the identification of contributed risk factors is crucial. In recent years, great attention has been paid to maternal factors. The reason is that maternal factors can directly affect fetus via intrauterine hypoxia. However, the results of this studies are conflicting. The purpose of this study was to evaluate the effect of maternal factors on the development of ROP.

Methods: In a prospective study, 150 premature infants with the gestational age of less than 32 weeks and birth weight of less than 1500 grams were examined. They divided into two groups based on ophthalmologic examination; those with ROP and those without ROP. Variables of study including maternal age, injection of corticosteroid in the last week of pregnancy, history of maternal diabetes mellitus, preeclampsia, hypertension, anemia, thyroid, renal, cardiovascular and rheumatologic diseases were compared between groups.

Results: Forty-seven infants (31.33 %) had ROP. The mean age of gestational age was 27.89 weeks in ROP group and 29.06 weeks in non-ROP group. The mean birth weight was 1180.53 grams in ROP group and 1079.44 grams in non-ROP group. There were no statistically important differences regarding to maternal factors between two groups.

Conclusion: The above mentioned maternal factors have no effect on the development of ROP.

Keywords: Retinopathy of prematurity, maternal factors, birth weight, gestational age

How to cite this article: Eftekhari A, Manouchehri V, Mosavi F, Jahanbani MA. [Evaluation of maternal factors for the development of retinopathy of prematurity]. Med J Tabriz Uni Med Sciences. 2021;43(2):173-178. Persian.
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Submitted: 11 Aug 2019
ePublished: 23 May 2021
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