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Med J Tabriz Uni Med Sciences Health Services. 2020;42(4): 440-446.
doi: 10.34172/mj.2020.066
  Abstract View: 649
  PDF Download: 299

Original Article

Diagnostic value of clinical symptoms and pulse oximetry for diagnosis of congenital heart disease in infants

Maliheh Kadivar 1 ORCID logo, Fateme Tahmasbi 2 ORCID logo, Mohammad Ali Zamani 1 ORCID logo, Razieh Sangsari 1* ORCID logo

1 Department of Pediatrics, Division of Neonatology – Faculty of medicine, Tehran University of Medical Sciences, Children’s Medical Center ,Tehran, Iran
2 Student Research Committee, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
*Corresponding Author: *Corresponding author; E-mail: , Email: Iran.raz3532@yahoo.com

Abstract

Background: Infants born with congenital heart disease (CHD) typically present different clinical manifestations which make this condition hard to diagnose. Considering serious complications arising from misdiagnosis, inventing new methods and/or improving traditional diagnostic approaches has always been a research objective.

Methods: In this cross-sectional analysis, which took place in Children's Medical Center in Tehran, 150 infants admitted to an intensive care unit were evaluated based on echocardiographic findings from 2015 to 2017. Echocardiography was done due to abnormalities in physical examination and/or oxygen saturation level.

Results: The sensitivity of clinical study value was 82% and the negative predictive value was 20%. The sensitivity of arterial oxygen saturation immediately after admission to the neonatal intensive care was 92%, the specificity was 34%, positive predictive value was 56% and negative predictive value was 25%.

Conclusion: In terms of high sensitivity, clinical symptom including tachypnea, cyanosis, arrhythmias, respiratory distress, cardiac murmur, or arterial oxygen saturation level in newborns may be useful for screening CHD. Among the clinical manifestations, cyanosis and respiratory distress are more valuable.


How to cite this article: Kadivar M, Tahmasbi F, Zamani MA, Sangsari R. [Diagnostic Value of Clinical Symptoms and Pulse Oximetry for diagnosis of Congenital Heart Disease in Infants]. Med J Tabriz Uni Med Sciences Health Services. 2020;42(4):440-446. Persian.
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Submitted: 16 Jun 2019
ePublished: 28 Oct 2020
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