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Med J Tabriz Uni Med Sciences Health Services. 2020;42(5): 564-571.
doi: 10.34172/mj.2020.080
  Abstract View: 1031
  PDF Download: 328

Original Article

Investigation of the physicochemical and pharmacognostical properties of Anzaroot (The manna of Astragalus sarcocola Dymock.) according to the World Health Organization

Hadi Esmaeeli 1 ORCID logo, Ali Davoodi 2 ORCID logo, Masoud Azadbakht 3 ORCID logo, Mohammad Azadbakht 2* ORCID logo

1 Research and Development Unit, NIAK Pharmaceutical Company, Gorgan, Iran
2 Department of Pharmacognosy, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran
3 Department of Plant Systematics, Institute of Higher Education, Sana Mazandaran, Sari, Iran
*Corresponding Author: *Corresponding author; E-mail: , Email: azadbakht110@gmail.com

Abstract

Background: Anzaroot is a manna produced from Astragalus sarcocola Dymock (Family Leguminosae) that is widely distributed in Fars, Kerman, Baluchestan and Hormozgan in Iran. Since the study of the physicochemical properties and quality control (QC) of herbal materials results in the validation and standardization for clinical uses, in accordance with World Health Organization (WHO) guidelines, it is necessary to carry out for Anzaroot which has indication in traditional medicine.

Methods: Anzaroot was identified and determinated scientific name by a systematic specialist after purchasing from Niak pharmaceutical co. in gorgan. Physicochemical and pharmacognostical properties of Anzaroot have been determinated According to the WHO guidlines.

Results: Anzaroot is a very bitter, crisp and fragile manna and non-stick in dry state, which is seen as separate binary grains under the microscope. The moisture content, foreign matter, sucrose content, total ash and water-soluble ash were reported 5.25 ± 0.2, 2.8 ± 0.2, 12.09 ± 0.04, 9.8 ± 0.5 and 2.9±0.15, respectively. It has significant foaming index, 72% Solublity in water and less than 50% in 96% ethanol and not swelling index. The levels of lead, mercury and cadmium were 0.0006, 0.0002 and 0.0007 ppm and total flavonoid content was reported 18.61 μg/ml with respect to standard Quercetin at 415 nm.

Conclusion: This study can be a novel idea for the discovery or development of pharmaceutical products based on Anzaroot of Iran and its diverse therapeutic properties, such as the common cold, contusion, and bone fracture in traditional medicine.


How to cite this article: Esmaeeli H, Davoodi A, Azadbakht M, Azadbakht M. [Investigation of the physicochemical and pharmacognostical properties of Anzaroot (The manna of Astragalus sarcocola Dymock.) according to the World Health Organization (WHO)]. Med J Tabriz Uni Med Sciences Health Services. 2020-2021;42(5):564-571. Persian.
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Submitted: 24 Jan 2019
ePublished: 30 Dec 2020
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