Logo-mj
Med J Tabriz Uni Med Sciences Health Services. 2021;42(6): 621-626.
doi: 10.34172/mj.2021.001

Scopus ID: 85131003481
  Abstract View: 801
  PDF Download: 259

Original Article

Comparing the efficacy of intense pulsed light combined with oral azithromycin versus oral azithromycin alone in the treatment of moderate to severe papulopustular acne vulgaris

Niloofar Afshari 1 ORCID logo, Mehdi Amirnia 1* ORCID logo, Davod Ahmadi 1 ORCID logo, Saeed Kashefi 2 ORCID logo, Vahideh Aghamohammadi 3 ORCID logo

1 Department of Dermatology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
2 Department of Surgery, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran
3 Department of Nutrition, Khalkhal university of Medical Sciences, Khalkhal, Iran
*Corresponding Author: *Corresponding author; E-mail: , Email: Mehamir46@gmail.com

Abstract

Background: Rising follicular keratin secretion, increasing sebum production, and Propionibacterium acnes are among the main etiology of acne vulgaris formation. Antibiotics are the predominant conventional treatment of acne. Antibiotic resistance is the main problem in the ordinary treatments of acne. Therefore, newer treatments are necessary. Intense pulsed light (IPL) is a novel therapeutic option with rapid application in this field.

Methods: Patients referred to us were randomized into two groups: group A (cases) and group B (controls). In addition to conventional antibiotic therapy, IPL was prescribed to group A while azithromycin alone was prescribed to group B. IPL treatment was performed weekly for five weeks and the patients were followed for three months. Declining inflammatory lesions count after the intervention was considered the remission scale.

Results: In group A, moderate, partial, and complete remission occurred in 4, 9, and 7 patients, respectively. In group B, moderate, partial, and complete remission occurred in 10, 7, and 3 patients, respectively. Statistically, the remission difference was meaningful between the two groups.

Conclusion: IPL with conventional antibiotics is an effective treatment choice in moderate to severe acne vulgaris but also is a more accelerating agent in treatment versus antibiotics alone.


How to cite this article: Afshari N, Amirnia M, Ahmadi D, Kashefi S, Aghamohammadi V. [Comparing the efficacy of intense pulsed light combined with oral azithromycin versus oral azithromycin alone in the treatment of moderate to severe papulopustular acne vulgaris]. Med J Tabriz Uni Med Sciences Health Services. 2021;42(6): 621-626. Persian.
First Name
 
Last Name
 
Email Address
 
Comments
 
Security code


Abstract View: 798

Your browser does not support the canvas element.


PDF Download: 259

Your browser does not support the canvas element.

Submitted: 14 Mar 2018
ePublished: 24 Feb 2021
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)