Influence of metabolic risk on adaptation of mean arterial pressure with endurance training and detraining: study of males with mild hypertension

Abstract

Background: According to uncommon adaptations in blood pressure observed in response to exercise, the standardized exercise prescriptions need to be reconsidered. Therefore, prediction of blood pressure adaptations in response to exercise and detraining is needed. Methods: In this study, 70 sedentary pre-hypertensive men randomized into experimental and control groups. Experimental subjects participated in aerobic training (24 sessions(3/wk) with 60 to 70% of MHR, 40 min/session) which followed by two weeks of detraining. The data were analyzed using Pearson correlation, Kappa test, ANOVA and stepwise regression. Results: After 8 weeks of training and following to detraining some of experimental subjects experienced decline in Mean Atrial Pressure (MAP), some had no changes and some had even experienced its increasing condition (P<0.05). All metabolic risk factors had significant changes after training and also detrainng, however; Zmets had significant changes just in those subjects with MAP decrease (P<0.05). The metabolic risk count and also Zmets were higher in both GR (x2=52.73, P=0.001) and BR subjects (x2=80.1, P=0.001) at baseline. MAP, age, BMI and also plasma HDL and LDL values at baseline were recognized as the significant predictors of Observed changes in MAP after training (R2=0.76, P<0.05). Conclusions: All the Metabolic risk factors are important in predicting the direction of MAP response to training, however; participation in aerobic exercise would not possibly lead to bad responding in those with high metabolic risk factors. However, more research remains to be done because of the lack of similar evidence in this area.