Association between Serum Iron, Ferritin, Hemoglobin and Hemostatic State with Short Term Mortality in Primary Intracerebral Hemorrhage

Abstract

Background & Objectives: Despite the high mortality and morbidity resulted from intracerebral hemorrhage (ICH), there is no definite cure for this type of stroke. This obvious disability rate necessitates some clinical and laboratory criteria to anticipate the short-term outcome. This study aimed to compare some blood and hemostatic indices between two groups with live and death outcomes. Materials and Methods: The subjects for this cohort study were selected via a consecutive based hospitalization. They were 90 patients with confirmed acute primary ICH (by CT scan). These patients divided into two groups, as live or dead at the end of the first week following ICH. All of the laboratory and clinical data were analyzed using independent T-test and the variance comparison test. Results: We studied 90 patients that consisted of 47 men and 43 women. Global comparison showed without considering gender, there were significant differences between two live and dead groups in the platelet count, iron, ferritin and ICH score. In the male group there was a significant difference in ferritin, Hb and ICH score between dead and live groups. Also in the female sub group, iron, ferritin and ICH score evinced meaningful difference among the two outcomes. Conclusion: Higher levels of iron and ferritin are related to short-term mortality in ICH patients.