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Med J Tabriz Uni Med Sciences Health Services. 2005;27(1): 27-29.
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Ophthalmology

Research

Effectiveness of Acetazolamide in Controlling of Intraocular Pressure after Extra Capsular Cataract Extraction and Posterior Chamber Lens Implantation with Hydroxypropyl methyl cellulose 2%

JAVADZADEH A, MOHAMMADZADEH M
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Abstract

Background and Objectives: Elevation of intra ocular pressure after cataract surgery is a common finding. For this purpose oral acetazolamide was used and effects of extracapsular cataract extraction and intraocular lens implantation with hydroxy propyl methyl cellulose were evaluated. Materials and Methods: A clinical trial was performed on 75 eyes of 75 patients. All of the patients underwent extracapsular cataract extraction and posterior chamber intraocular lens implantation with hydroxy propyl methyl cellulose 2%. Acetazolamide was used 4 and 12 h after operation in the case group but not the control group. Results: Pre operative IOP were 14.03 ± 2.85 mmHg in acetazolamide group and were 13.15 ±2.5 mmHg in control group. Difference of mean IOP before and 7h after operation were + 0.5 ± 3.41 mmHg in acetazolamide group ( not significant ) and were + 4.94 ± 3.71 mmHg in control group ( p= 0.0001 ). Difference of mean IOP before and 24h after operation were - 0.39 ± 2.66 in acetazolamide group ( not significant ) and were 5.17 ± 4.05 mmHg in control group ( p= 0.0001 ). Conclusion: Use of acetazolamide after extra capsular cataract extraction and intra ocular lens implantation with hydroxy propyl methyl cellulose can prevent of IOP elevation. Therefore routine use of acetazolamide control post operative IOP may be taken into consideration.
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Submitted: 09 Jul 2013
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