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Med J Tabriz Uni Med Sciences Health Services. 2006;27(4): 125-128.
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Pediatrics

Research

A 4-month infant with Chylomicron Retention disease(Anderson's Disease): Case Report

Abstract

Anderson's disease or chylomicron retention disease is a rare genetic disorder associated with fat malabsorption and is characterized by severe diarrhea, steatorrhea, failure to thrive and, finally, ophthalmic and neurologic problems in infants. Gastrointestinal symptoms appear during the first months of life and if this disease is not diagnosed and treated early, ophthalmic and neurologic manifestations will appear due to lack of vitamins A and E during the second decade of life. In this paper a 4-month female is introduced.This infant has a history of gastrointestinal manifestations such as chronic diarrhea, fatty stool and failure to thrive which started at the age of 1.5-month and was admitted in Tabriz children's hospital due to fever and cough. After necessary paraclinical evaluations pneumona was diagnosed and the patient was treated with antibiotics. In order to find the cause of FTT, some diagnostic evaluations were carried out during her hospitalization and, ultimately, after serological examinations, eye examination, upper GI-tract endoscopy and study of small intestinal biopsies, Anderson's disease or chylomicron retention disease was diagnosed and the patient received the necessary treatments.
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Submitted: 30 Jan 2011
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