Abstract
Background and objectives: Pityriasis Rosea is a relatively common skin disease that its etiology and treatment has not cleary defined .The aim of this study was to avaluate the efficacy of oral erythromycin in patients with Pityriasis Rosea .
Materials and Methods: Fifty patients were selected which were the divided into 2 groups. In group A (test group) the patients were treated by erythromycin while in group B (plecebo group) the patients neceived chlorpheniramin or diphenhydramin. Duration of therapy in both groups were 14 days. Both groups were compasable with regard of age, sex and aveag duration of diseaze at the time of reposting to the clinic. At the end of 2 weeks , the responses were categorized as complete response , partial response or no response .
Results: Upper respiratory tract infection before the appearance of the skin lesions was reported in 72% of all patients .Complete response was observed in 16 patients (64%) in the treatment group(A) and none in the second group(B) ( P= 0/0001). There was not any side effect in the treatment period with oral erythromycin .
Conclusion: oral erythromycin was effective and safe in the treatment of the patients with pityriasis rosea.