Abstract
Squamous cell carcinoma of scrotum is a rare disease. Risk factors are occupational contacts, low health conditions, psoriasis, treatment with PUAV, and HPV (human papilloma viruses). In this paper a non occupational case is presented witch is not associated with other known risk factors. The patient is a 50 years man which was referred from dermatology clinic with a exophytic cutaneous lesion without any lymphatic or other organ involvement. The lesion was exissed completely .The pathologic report was well differentiated squamous cell arcinoma. In two years follow-up the patient has no complication and is disease free.