Tabriz University of Medical Sciences Medical Journal of Tabriz University of Medical Sciences 2783-2031 37 3 2015 08 05 Prevalence of Shiga Toxin-Producing Genes in Escherichia Coli Isolated From Patients with Urinary Tract Infections in Khorramabad 50 55 EN Fereydoun Mansouri Nemat Shams Ehsan Rashidian Journal Article 2014 09 15 2014 10 11 Background and Objectives: Shiga toxins (verotoxin) is one of the most important bacterial toxin produced by the Escherichia coli (O157: H7 and nonO157: H7), and is responsible for various diseases in humans and animals. Hemolytic uremic syndrome (HUS) is serious human diseases that occur because of these toxins. There is no comprehensive information in this regard, here will studied the prevalence of these genes among the E- coli isolated from urine samples in Khorramabad. Material and Method: The study is based on 146 Escherichia coli isolates of Patients with symptoms of urinary tract infection referred to clinical laboratories in Khorramabad during 90-1389. We used we identified the isolates by biochemical tests .The Multiplex PCR Multiplex PCR method were used to presence of genes. Results: A total of 117 (13/80%) of the women and 29 (86/19) of the men and none of them carried both stx1and stx2. Conclusion: Shiga toxin-producing E. coli isn't responsible for urinary tract infection in KhorramabadAlthough the frequency of these genes in urine samples is low, but evaluation of the other human and animal samples in different parts of the country is essential.