Tabriz University of Medical Sciences Medical Journal of Tabriz University of Medical Sciences 2783-2031 33 6 2012 03 11 A Case of Neuroachantocytosis with Partial Response to Clozapine and Botulinum Toxin Injection 103 106 EN Hormoz Ayromloo Safa Najmi Mazyar Hashemilar Journal Article 2012 03 12 Neuroachantocytosis, a form of hereditary chorea, is a degenerative multisystem disease presenting with several types of abnormal movements such as dystonia and chorea together with other neurological problems including neuropathy, amyotrophy, seizure and ataxia. Here, we report a 52-year old male with recurrent oromandibular dystonic attacks together with progressive chorea at limbs, seizure, ataxia, and depression. With diagnosis of neuroachantocytosis, the patient received clozapine and botulinum toxin injection resulting in partial response.